Genetic thrombophilic mutations among couples with recurrent miscarriage
نویسندگان
چکیده
منابع مشابه
The Prevalence of Common Mutations in Thrombophilic Patients in Iranian Population with Recurrent Miscarriage
Background and Aims: To date, several factors have been reported in recurrent miscarriage. Genetic mutations are the most important causative factors in women. Fetal thrombotic vasculopathy is a new described placental alteration with varying degrees of involvement and often associated with adverse prenatal outcomes. The diagnosis is made histologically and so is postnatal, which makes it a cha...
متن کاملThrombophilic gene mutations in women with repeated spontaneous miscarriage.
AIM One of the main problems concerning repeated spontaneous miscarriage (RSM) is the etiological diagnosis. The relation of thrombophilia to RSM is a matter of debate. In this case-control study, we determined the percentages of three thrombophilic mutations (factor V leiden, prothrombin, and methylenetetrahydrofolate reductase) amongst 20 cases with RSM and 20 control normal parous women. R...
متن کاملThe Investigation and Treatment of Couples with Recurrent Miscarriage
Recurrent miscarriage is a distressing problem that affects 1% of all women. This incidence is greater than that expected by chance alone, since 10–15% of all clinically recognised pregnancies end in a miscarriage and the theoretical risk of three consecutive pregnancy losses is 0.34%. Hence, only a proportion of women presenting with recurrent miscarriage will have a persistent underlying caus...
متن کاملGenetic Studies on Recurrent Miscarriage
____________________________________________________________ 9 Introduction ________________________________________________________ 11 Review of the literature ________________________________________________ 12 1 Early human embryonic development _______________________________ 12 1.1 Fertilization __________________________________________________ 12 1.2 Implantation ________________________...
متن کاملThe Effect of Vitamin E and Selenium on Sperm Chromatin Quality in Couples with Recurrent Miscarriage
Background and Aims: Due to the paucity of studies, association between the morphology and function of sperm and recurrent miscarriage (RM) is not yet completely known. Increased reactive oxygen species and decreased antioxidant levels in men have been shown to be associated with RM. Recently it has been accepted that antioxidant therapy can approve sperm parameters. The goal of this study was ...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2006
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/dei466